Large UPS plane exploded around 5.15pm as it departed Louisville Muhammad Ali International Airport, heading toward Daniel K Inouye International Airport in Honolulu

The MD-11 cargo plane exploded as it took off from a Louisville, Kentucky airport on Tuesday, crashing back to the tarmac in flames

On takeoff the plane crashed back into the runway, leaving a blaze in its wake, going on to strike two local businesses

The plane was also fueled with 38,000 gallons at the time, due to the lengthy trip to Hawaii sparking a massive fire that spread to cover five miles

Fatalities includes the three crew members onboard the flight at the time

An update Wednesday, said the number of deaths has risen to 9, with the number expected to rise

11 people were injured, and at least 16 people still missing

Viral video showed a ball of fire emanating from the center of the plane within minutes of UPS Flight 2976 departing the runway at Louisville, Kentucky airport Tuesday evening

At this time nine people have been confirmed dead, with dozens injured after a large UPS plane exploded as it took off from a Louisville, Kentucky airport.
The MD-11 plane exploded as it departed Louisville Muhammad Ali International Airport, heading toward Daniel K Inouye International Airport in Honolulu.
UPS Flight 2976 was carrying three crew members and 50,000 gallons of jet fuel when it exploded in a massive fireball around 5:15 p.m. on Tuesday just 13 minutes after takeoff, according to the Federal Aviation Administration.
The air disaster caused a massive fire, with giant plumes of smoke spanning miles around the airport.

The aircraft was a UPS MD-11 plane with three crew members onboard. The explosion caused a fire to spread to cover the area around the airport in Louisville

Viral video shared on social media shows the aircraft attempting to takeoff with a ball of fire emanating from its left wing. Within moments, the aircraft plane exploded.
Dashcam footage also showed the plane crashing back into the runway, leaving a blaze in its wake.
The careening fireball struck two local businesses, Kentucky Petroleum Recycling and Grade A Autoparts store.
In an update Wednesday, Kentucky Gov. Andy Beshear said the number of deaths has risen to 9, with the number expected to rise. The governor said 16 different families have reported loved ones unaccounted for, as a significant search and rescue mission continued Wednesday morning.

The plane with capacity 50,000 gallons of fuel, due to the lengthy trip to Hawaii, sparked a massive fire that spread to cover five miles, destroying two local businesses, Kentucky Petroleum Recycling and Grade A Autoparts

Four of the people killed were on the ground, Louisville Fire Chief Brian O’Neill said. The victims have not been identified.
There were three crew members onboard the flight at the time, UPS officials have confirmed. But it is unclear whether the fatalities were members of the crew.
‘From the videos I’ve seen, I’m very concerned for them, but I’m still praying,’ Beshear said at a news conference Tuesday night.  ‘It may be some time until we can account for everyone,’ he warned.
The plane with a full capacity fuel payload, due to the lengthy trip to Hawaii, sparked a massive fire that spread to cover five miles.
The initial number of injured persons was put at 11, two of whom were listed in critical condition on Tuesday night.

It has been said that an engine fell off as UPS Flight 2976 took off. What appears to be an engine from the crashed MD-11 is seen here lying on the runway following the horrifying crash on Tuesday night

Immediately after the crash on Tuesday morning, Louisville Metro Police then announced on social media that several agencies are responding to the scene south of the airport as authorities urged community members to avoid the area. 
They said it remained an active scene with ‘smoke and debris’, as they issued a shelter-in-place order which at one point covered much of the city.
‘Please remain away from the area until further notice,’ the police department urged as authorities secured the buildings.

Authorities said it remains an active scene with ‘smoke and debris’, but thee airport resumed operations Wednesday morning with flights canceled Tuesday prioritized for departure. Some Wednesday flights remained grounded

By nightfall Tuesday, an order warning people to shelter in place was reduced from a five-mile radius from the airport to a one-mile radius as crews worked to contain the blaze.
Louisville airport resumed operations Wednesday morning with flights canceled Tuesday prioritized for departure. However some Wednesday flights remained grounded.
Those who found debris from the crashed plane, including burned packages, have been urged to fill out a form.